期刊论文

Fei Yang

英文

Water Research

0043-1354

2023

229

119397

10.1016/j.watres.2022.119397

CRediT authorship contribution statement Jia Wei: Conceptualization, Methodology, Visualization, Writing – original draft, Writing – review & editing. Zhou Pengji: Data curation, Software, Visualization, Methodology. Jiajia Zhang: Data curation, Software, Visualization. Tangjian Peng: Supervision, Writing – review & editing. Jiayou Luo: Supervision, Writing – review & editing. Fei Yang: Conceptualization, Supervision, acquisition, Investigation, Methodology, Resources, Writing – review & editing.

本校为其他机构

Microcystins (MCs) are harmful to the ecology and public health. Some bacteria can degrade MCs into Adda, but few can destroy Adda. Adda is the key bioactive moiety of MCs and mainly contributes to hepatotoxicity. We had previously isolated an indigenous novel bacterial strain named Sphingopyxis sp. YF1 that can efficiently degrade MCs and its key bioactive moiety Adda, but the mechanisms remained unknown. Here, the biodegradation mechanisms and pathways of Adda were systematically investigated using multi-omics analysis, mass spectrometry and ...