To elucidate the mechanism of damage caused by hyphae and organic acids produced by Aspergillus Niger on the surface and internal structure of uranium ore, direct uranium leaching, indirect uranium leaching and semi-direct uranium leaching were conducted, and the surface morphology, strength, mineral crystallinity, porosity, and permeability of the ore were analyzed. The results demonstrated that the combination of biomechanical forces exerted by hyphae and the complexation effects of organic acids led to the dissolution of SiO2 and other subst...