期刊论文

Haibo Mei

英文

Rapid Communications in Mass Spectrometry

0951-4198

2022

36

21

e9374-

10.1002/rcm.9374

This work was supported by funding from the Hunan Province Natural Science Foundation for Youths (2021JJ40271), the “Young Talents” of “1233 program” of Hunan Children-s Hospital, National Key Clinical Specialty Construction Project - Pediatric Surgery of Hunan Children's Hospital (XWYF [2022] No. 2), and the Hunan Science and Health Combination Funding (2022JJ70007).

本校为第一机构

RATIONALE: The exact etiology and pathogenesis of congenital pseudarthrosis of tibia (CPT) are not clear. Quantitative proteomics analysis plays a vital role in disease pathology research. Tandem mass tag (TMT)-based proteomics techniques were employed to identify and analyze the differentially expressed proteins (DEP) in the tibia periosteum tissues of CPT patients. METHODS: The samples were divided into three groups: CPT with NF1 group, CPT without NF1 group (non-NF1-CPT), and control group (patients with open tibial fracture). A fold change ...