期刊论文

中文

心肺血管病杂志

1007-5062

2018

37

2

112-116

10.3969/j.issn.1007-5062.2018.02.007

首都医科大学基础临床合作课题（16JL42） 2016年安贞医院院长基金资助培育项目（2016P01） 南华大学校内博士启动基金项目（2015XQD08）

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目的:探讨代谢综合征组分与高血压患者早期肾损害的关系。方法:对399例肾功能正常且未治疗的原发性高血压患者进行横断面调查,测定身高、体质量、腰围、血脂、血糖等生化指标。根据Cockcroft-Gault公式计算肾小球滤过率（e GFR）诊断CKD,采用国际糖尿病联盟（IDF）全球共识定义诊断代谢综合征（MS）,将患者分为MS组（n=246）和非MS组（n=153）,比较两组患者临床特点差异;分析MS组分与高血压早期肾损害的关系。结果:（1）MS组BMI、腰围、TG、HDL-C、舒张压、尿酸、肌酐值、尿微量白蛋白/尿肌酐（ACR）值均高于非MS组,MS组e GFR水平低于非MS组（P

Objective:To explore the relationship between the number of metabolic syndrome (MS) components and early renal damage in patients with hypertension.Methods:A total of 399 consecutive untreated middle-aged hypertensive patients with either normal renal function were included in the cross-sectional study.Height,body weight,waist circumference,and biochemical indicators such as serum lipid and blood glucose were measured.Stage of CKD was determined by estimated glomerular filtration rate (eGFR) based on Cockcroft-Gault formula.MS was diagnosed acc...