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Association between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome: A systematic review and meta-analysis

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成果类型:
期刊论文
作者:
Liu, Ai Ling;Xie, Hui Jun;Xie, Hong Yan;Liu, Jun;Yin, Jie;...
通讯作者:
Peng, Cui Ying
作者机构:
[Yin, Jie; Xie, Hui Jun; Xie, Hong Yan; Hu, Jin Song; Peng, Cui Ying; Liu, Jun; Liu, Ai Ling] Univ South China, Inst Biol Sci, Sch Pharmaceut & Biol Sci, Hengyang 421001, Hunan, Peoples R China.
[Peng, Cui Ying; Liu, Ai Ling] Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.
[Peng, Cui Ying; Liu, Ai Ling] Key Lab Biol Toxicol & Ecol Restorat Hengyang Cit, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Peng, Cui Ying] U
[Peng, Cui Ying] H
Univ South China, Inst Biol Sci, Sch Pharmaceut & Biol Sci, Hengyang 421001, Hunan, Peoples R China.
Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Polycystic ovary syndrome;FTO;Meta-analysis;Polymorphism
期刊:
BMC Medical Genetics
ISSN:
1471-2350
年:
2017
卷:
18
期:
1
页码:
1-7
基金类别:
National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [31371277]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2016JJ6126]
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
Background: Up to now, numerous case-control studies have reported the associations between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome (PCOS), however, without a consistent result. Hence we performed current systematic review and meta-analysis to clarify the controversial results. Methods: Case-control studies reporting the relationship of rs9939609 A/T polymorphism and PCOS published before April 2015 were searched in Pubmed database without language restriction. Data was analyzed by Rev...

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