Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2020JJ4082]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81573193]
机构署名:
本校为第一机构
院系归属:
公共卫生学院
摘要:
Beryllium and its compounds are systemic toxicants that are widely applied in many industries. Hydrogen sulfide has been found to protect cells. The present study aimed to determine the protective mechanisms involved in hydrogen sulfide treatment of 16HBE cells following beryllium sulfate-induced injury. 16HBE cells were treated with beryllium sulfate doses ranging between 0 and 300 μM BeSO4. Additionally, 16HBE cells were subjected to pretreatment with either a 300 μM dose of sodium hydrosulfide (a hydrogen sulfide donor) or 10 mM DL-proparg...