Project of Research-based Learning and Innovative Experiments for Undergraduate Students grant [2018XJXZ145]
机构署名：
本校为第一且通讯机构
院系归属：
医学院
摘要：
Acute liver failure (ALF) is a devastating clinical syndrome with a high mortality rate if not treated promptly. Previous studies have demonstrated the beneficial effects of hydrogen sulfide (H(2)S) on the brain and liver. The present study aimed to investigate the potential protective effects of H(2)S in ALF. A mouse model of ALF was established following treatment with thioacetamide (TAA). Mice with TAA-induced ALF were intraperitoneally injected with 30 or 100 µmol/kg/day sodium hydrosulfide (NaHS; a H(2)S donor drug) for two weeks. Accordi...
