Purpose: The goal of this study was to evaluate the biomechanical effects such as sonoporation or permeability, produced by ultrasound-driven microbubbles (UDM) within microvessels with various parameters. Methods: In this study, a bubble-fluid-solid coupling system was established through combination of finite element method. The stress, strain and permeability of the vessel wall were theoretically simulated for different ultrasound frequencies, vessel radius and vessel thickness. Results: the bubble oscillation induces the vessel wall dilatio...