Association between SOX gene family expression, DNA methylation, and miRNA regulation in lung adenocarcinoma progression

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成果类型：

期刊论文

作者：

Wang, Haidao;Hu, Yiming;Lu, Haibin;Wu, Zhijie;Zhang, Yixiang

通讯作者：

Wang, HD

作者机构：

[Wang, Haidao] Fujian Med Univ, Quanzhou Hosp 1, Quanzhou 362000, Fujian, Peoples R China.

[Lu, Haibin; Hu, Yiming; Wu, Zhijie] Fujian Med Univ, Fuzhou 350108, Fujian, Peoples R China.

[Hu, Yiming] Natl Ctr Chron & Noncommunicable Dis Control & Pre, Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China.

[Lu, Haibin] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Peoples R China.

[Zhang, Yixiang] Fujian Med Univ, Affiliated Hosp 2, Quanzhou 362000, Fujian, Peoples R China.

通讯机构：

[Wang, HD ] F

Fujian Med Univ, Quanzhou Hosp 1, Quanzhou 362000, Fujian, Peoples R China.

语种：

英文

关键词：

SOX gene family;Lung adenocarcinoma;Prognosis;Gene expression

期刊：

Discover Oncology

ISSN：

2730-6011

年：

2025

卷：

期：

页码：

1-12

DOI：

10.1007/s12672-025-01892-x

基金类别：

None.

机构署名：

本校为其他机构

院系归属：

公共卫生学院

摘要：

OBJECTIVE: To analyze the expression of the SOX gene family in lung adenocarcinoma and its impact on the prognosis of lung adenocarcinoma patients using tumor databases. METHODS: The cBioPortal database was used to retrieve and analyze the mutation frequencies and variants of 10 genes in the SOX gene family in lung adenocarcinoma tissues. Using clinical information from the Kaplan-Meier plotter database, the potential prognostic values of 10 genes in the SOX gene family in lung adenocarcinoma patients were further explored. The UALCAN database ...

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Association between SOX gene family expression, DNA methylation, and miRNA regulation in lung adenocarcinoma progression

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