Acknowledgments This work was supported by the National Natural Science Foundation of China (81670429, 91839103, to ZSJ), International Joint Laboratory for Arteriosclerotic Disease of Hunan Province (2018WK4031), Special for Construction of Innovative Provinces in Hunan Province (2020SK2105, to ZSJ) and “Double First-Class” project for innovative Group of Basic Medicine, University of South China (to ZSJ).