期刊论文

Molecular Characterization of Five Strains of Intestinal Adenovirus 41(HAdV-41) Isolated in Shenzhen,China in 2022

中文

病毒学报

1000-8721

2023

39

6

1578-1585

10.13242/j.cnki.bingduxuebao.004408

“十三五”国家科技重大专项(2018ZX10713001)。

本校为第一机构

人腺病毒41型(Human adenovirus,HAdV-F41)是儿童胃肠炎的常见病因,但目前HAdV-F41的分子特征尚未得到详细研究。本研究选取2022年2-5月的5个儿童急性腹泻患者的粪便样本,进行高通量测序得...展开更多 人腺病毒41型(Human adenovirus,HAdV-F41)是儿童胃肠炎的常见病因,但目前HAdV-F41的分子特征尚未得到详细研究。本研究选取2022年2-5月的5个儿童急性腹泻患者的粪便样本,进行高通量测序得到全基因组序列。5个深圳株与参考株Tak(DQ315364)的核苷酸序列同一性为97.5%~98.6%,在四个重要结构基因中无核苷酸的插入和缺失,有2株在Hexon基因可见ε抗原表位发生突变,可能使毒株出现免疫逃逸,出现显著突变...

Human adenovirus type 41(HAdV-F41) is one of common causes of gastroenteritis in children,but the molecular characteristics of HAdV-F41 have not been studied in detail yet.This study selected fecal samples from 5 children with acute diarrhea from February to May 2022 an...MORE Human adenovirus type 41(HAdV-F41) is one of common causes of gastroenteritis in children,but the molecular characteristics of HAdV-F41 have not been studied in detail yet.This study selected fecal samples from 5 children with acute diarrhea from February to May 2022 and ...