期刊论文

Tan, Ni

英文

Journal of Pharmaceutical and Biomedical Analysis

0731-7085

2020

180

113036

10.1016/j.jpba.2019.113036

This work was supported by the Scientific Research Project of Education Department of Hunan (No.17C1359); and the Research Learning and Innovative Experimental Program of Hunan/University South of China (S201910555016, X2019070, X2019071).

本校为第一且通讯机构

In this study, a new type of drug delivery carrier, the hollow magnetic silybin molecularly imprinted polymer (HMMIP) with a unique core-shell structure where the hollow magnetic core Fe3O4 was wrapped by mesoporous silica and imprinted layer, was prepared from methacrylic acid (MAA, functional monomer), ethylene glycol dimethacrylate (EGDMA, cross-linker), and silybin (a drug template) by reverse atom radical transfer polymerization method (RATRP), and characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer (XRD), vibrating sample magnetometer (VSM), thermo-grav...