The authors acknowledge the grants of the Provincial Natural Science Foundation of Hunan Province (2021JJ50014), Scientific Research Project of Hunan Provincial Health Commission (202105012137), Municipal Science project of Hengyang City in Hunan Province (202002042122), National Natural Science Foundation of China (81402169), Educational Committee Foundation of Hunan Province (19C1616), Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control (2014-5) and Construct Program of the Double First-Class discipline of University of South China (2020SYL).