期刊论文

Yin, Kai

英文

Clinica Chimica Acta

0009-8981

2013

424

245-252

10.1016/j.cca.2013.06.006

The authors gratefully acknowledge the financial support from the National Natural Sciences Foundation of China ( 81070220 and 81170278 ), and Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Human Province, China ( 2008-244 ).

本校为第一且通讯机构

Atherosclerosis is a chronic disease characterized by the deposition of excessive cholesterol in the arterial intima. Macrophage foam cells play a critical role in the occurrence and development of atherosclerosis. The generation of these cells is associated with imbalance of cholesterol influx, esterification and efflux. CD36 and scavenger receptor class A (SR-A) are mainly responsible for uptake of lipoprotein-derived cholesterol by macrophages. Acyl coenzyme A:cholesterol acyltransferase-1 (ACAT1) and neutral cholesteryl ester hydrolase (nCE...