Natural Science Foundation of Hunan Province [42377076]; National Natural Science Foundation of China [2023JJ50129]; Natural Science Foundation of Hunan Province [202002042158]; Basic Applied Research Special Project of Hengyang; Independent Research Project of the China Academy of Radiation Protection (2022 Platform Open Fund Project of the National Key Laboratory of Radiation Environment and Health for Environmental Protection -4)
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
公共卫生学院
摘要:
This study reveals the transformation of the Super Uranyl-binding Protein (SUP) gene with high uranium selectivity and binding affinity into Deinococcus Radiodurans, a genetically modified bacterium with high uranium adsorption capacity and resistance to radiation. The optimal adsorption conditions and mechanism of Deino-SUP for uranium under different environmental conditions were investigated. The results demonstrated the successful construction of Deino-SUP, a recombinant strain with excellent uranium adsorption capacity and radiation resistance. The adsorption of uranium by Deino-SUP is ma...