A resonance light scattering (RLS) method for the detection of fluoride ions in aqueous solution is reported in this paper. Uranyl-bis-salophen (UBS), a binuclear uranyl complex prepared by the reaction of uranyl with a ditopic tetradentate Schiff base ligand bis-salophen, was used for the experiment. It is found that after UBS self-assembled with pyrophosphate to form a uranyl coordination supramolecular polymer (SP), the system produced a strong RLS signal. When fluoride ions coexisted with UBS, the formation of SP was inhibited due to which ...