Construction of HClO activated near-infrared fluorescent probe for imaging hepatocellular carcinoma

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Songjiao;Wang, Peipei;Yang, Ke;Liu, Ying;Cheng, Dan;...

通讯作者：

He, Longwei(helongwei0110@163.com);Cheng, Dan(flychand0110@163.com)

作者机构：

[Liu, Ying; Yang, Ke; He, Longwei; Wang, Peipei; Li, Songjiao] Univ South China, Hengyang Med Sch, Canc Res Inst, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Hengyang 421001, Peoples R China.

[Cheng, Dan] Univ South China, Affiliated Nanhua Hosp, Hengyang Med Sch, Clin Res Inst, Hengyang, Peoples R China.

通讯机构：

[Dan Cheng] C

[Longwei He] H

L. He

Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Cancer Research Institute, Department of Pharmacy and Pharmacology, Hengyang Medical School, University of South China, Hengyang, 421001, China

email: helongwei0110@163.com

语种：

英文

关键词：

Animals;Carcinoma, Hepatocellular;Fluorescent Dyes;Hypochlorous Acid;Liver Neoplasms;Mice;Optical Imaging;Tumor Microenvironment;Biocompatibility;Cancer cells;Chlorine compounds;Cytology;Diagnosis;Diseases;Fluorescence imaging;Fluorescence spectroscopy;Infrared devices;Optical properties;Probes;fluorescent dye;hypochlorous acid;MBH 1;MBH melatonin;unclassified drug;fluorescent dye;hypochlorous acid;Fluorescent probes;Hepatocellular carcinoma;Hepatocytes;Hypochlorous acids;Imaging experiments;Liver cancers;Near Infrared;Near-infrared;Near-infrared fluorescent;Overall survival;animal cell;animal experiment;animal model;animal tissue;Article;biological monitoring;cancer surgery;controlled study;drug synthesis;early cancer diagnosis;female;Hep-G2 cell line;HK-2 [Human kidney] cell line;human;human cell;HUVEC cell line;in situ hybridization;in vivo study;L-02 cell line;live cell imaging;liver cell carcinoma;mouse;nonhuman;RAW 264.7 cell line;animal;diagnostic imaging;fluorescence imaging;liver cell carcinoma;liver tumor;metabolism;procedures;tumor microenvironment;Cells

期刊：

Analytica Chimica Acta

ISSN：

0003-2670

年：

2023

卷：

1252

页码：

341009

DOI：

10.1016/j.aca.2023.341009

基金类别：

Research Foundation of Education Bureau of Hunan Province, (22B0403) Natural Science Foundation ofHunan Province, (2022JJ10042, 2022JJ30484, 2022JJ40358) Natural Science Foundation ofHunan Province University of South China, USC, (201RGC012, 220XQD030) University of South China, USC State Key Laboratory of Chemo/Biosensing and Chemometrics, (2021013, 2021015) State Key Laboratory of Chemo/Biosensing and Chemometrics

机构署名：

本校为第一机构

院系归属：

医学院

药学与生物科学学院

摘要：

Hepatocellular carcinoma (HCC) is one of the most common malignancies in the liver with poor prognosis. In order to improve the prognosis and overall survival of patients with HCC, it is important to identify it at early stage and resect it precisely. Cell microenvironment, active compounds, and enzymes may change during the cancerization of hepatocytes. Hypochlorous acid (HClO), one of the most significant signal molecules in the cellular signaling pathway, plays an important role in many cellular processes. To detect and treat liver cancers, ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Construction of HClO activated near-infrared fluorescent probe for imaging hepatocellular carcinoma

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问