National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30770689]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [10JJ2009]; Hunan Provincial Education DepartmentHunan Provincial Education Department [09C831]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
药学与生物科学学院
摘要:
Recent evidence has demonstrated that the ventromedial prefrontal cortex (vmPFC) is a critical site of the neural circuits underlying fear extinction memory. The ventrolateral prefrontal cortex (vlPFC) is not directly involved in extinction processes within the aversive domain. However, most of the current cumulated data on extinction is based on a classical delay fear conditioning paradigm in which the interval between the onset of the conditioned stimulus (CS) and the unconditioned stimulus (US) is consistent in a given protocol. In the present study, we developed a modified delay fear condi...