Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Ning, Zhi-Hong;Wang, Xiu-Heng;Zhao, Yue;Ou, Yun;Yang, Jia-Yan;...

通讯作者：

Hu, HJ

作者机构：

[Zhao, Yue; Hu, Heng-Jing; Ou, Yun; Ning, Zhi-Hong; Tang, Hui-Fang; Yang, Jia-Yan] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Cardiovasc Med, 69 W Chuang Shan Rd, Hengyang 421001, Hunan, Peoples R China.

[Wang, Xiu-Heng] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Med Record, Hengyang 421001, Hunan, Peoples R China.

[Hu, Heng-Jing] Univ South China, Hengyang Med Sch, Dept Cardiovasc Dis, Hengyang 421001, Hunan, Peoples R China.

[Hu, Heng-Jing] Univ South China, Hengyang Med Sch, Key Lab Atherosclerosis Hunan Prov, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Hu, HJ ] U

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Cardiovasc Med, 69 W Chuang Shan Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Antioxidants;Ferroptosis;Iron metabolism;Lipid peroxidation;Organ fibrosis;Therapeutic strategies

期刊：

International Immunopharmacology

ISSN：

1567-5769

年：

2025

卷：

151

页码：

114341

DOI：

10.1016/j.intimp.2025.114341

基金类别：

This work was supported by the National Natural Science Foundation of China (grant no. 81700306 ), Natural Science Foundation of Hunan Province of China (grant no. 2022JJ30528 ), Scientific Research Foundation of Hunan Provincial Education Department (grant no. 21B0408 ), Key Project of Hunan Provincial Science and Technology Innovation (grant no. 2020SK1013–2 ), Key Guidance Topics of Hunan Provincial Health Commission (grant no. C202303019182 ) and National Key Clinical Specialty Scientific

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Ferroptosis, a form of iron-dependent regulated cell death, has emerged as a critical mechanism in the pathogenesis of organ fibrosis. This review aims to provide an overview of the molecular mechanisms underlying ferroptosis and its contribution to fibrosis in various organs, including the liver, lung, heart, and kidneys. We explore how dysregulated iron metabolism, lipid peroxidation, and oxidative stress contribute to ferroptosis and subsequent tissue damage, promoting the progression of fibrosis. In addition, we highlight the complex interplay between ferroptosis and other cellular process...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问