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Necrostatin-1: a promising compound for neurological disorders

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成果类型:
期刊论文
作者:
Chen, Ke-qian;Wang, Shu-zhi;Lei, Hai-bo*;Liu, Xiang
通讯作者:
Lei, Hai-bo;Liu, X;Wang, SZ
作者机构:
[Lei, Hai-bo; Lei, HB; Liu, Xiang; Chen, Ke-qian] Xiangtan Cent Hosp, Dept Clin Pharm, Xiangtan, Peoples R China.
[Wang, Shu-zhi; Wang, SZ] Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.
通讯机构:
[Lei, HB; Liu, X ] X
[Wang, SZ ] U
Xiangtan Cent Hosp, Dept Clin Pharm, Xiangtan, Peoples R China.
Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
necroptosis;necrostatin-1;neurological disorders;Apoptosis;necrostatins
期刊:
Frontiers in Cellular Neuroscience
ISSN:
1662-5102
年:
2024
卷:
18
页码:
1408364
基金类别:
The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.
机构署名:
本校为其他机构
院系归属:
药学与生物科学学院
摘要:
Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurologica...

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