期刊论文

Jiang, ZS

英文

DNA AND CELL BIOLOGY

1044-5498

2022

41

3

262-275

10.1089/dna.2021.0943

This work was supported by National Key Research and Development Program of China (2019YFA0801601 to Z.-S.J.), National Natural Science Foundation of China (81670429, 91839103 to Z.-S.J.), International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province (2018WK4031), Special Funding for Construction of Innovative Provinces in Hunan Province (2020SK2105 to Z.-S.J.), ‘‘Double First-Class’’ project for innovative Group of Basic Medicine, University of South China (to Z.-S.J.), and Hunan Graduate Scientific Research Innovation Project (CX20210958 to N.-H.D.).

本校为第一且通讯机构

Inflammation is a double-edged sword. The moderate inflammatory response is a fundamental defense mechanism produced by the body's resistance to dangerous stimuli and a repair process of the body itself. Increasing studies have confirmed that the overactivation of the inflammasome is involved in the occurrence and development of inflammatory diseases. Strictly controlling the overactivation of the inflammasome and preventing excessive inflammatory response have always been the research focus on inflammatory diseases. However, the endogenous reg...