Education Department of Hunan Province of China [21B0421]; Natural Science Foundation of Hunan Province of China [2023JJ40533, 2022JJ40354]; National Natural Science Foundation of China [21977042]
机构署名：
本校为第一且通讯机构
院系归属：
化学化工学院
摘要：
The development of organelle-targeted probes that enable specific recognition and detection Cysteine (Cys) may provide an effective way to explore physiological processes and pathological mechanisms associated with the related diseases. In this work, an acetylpyrene-based fluorescent probe CP-1 was designed and syn-thesized for detecting Cys in vitro and in vivo. The probe exhibited a noticeable fluorescence blue shift upon the addition of Cys under UV light, attributed to the mechanism of the nucleophilic addition reaction. The response mechanism for Cys was studied by time-dependent density ...
