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Protective role of melatonin against radiation-induced disruptions in behavior rhythm of zebrafish ( danio rerio) )

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成果类型:
期刊论文
作者:
Zhao, Weichao*;Yao, Jing;Liu, Yu;Mao, Liang;He, Chuqi;...
通讯作者:
Zhao, Weichao;Long, DX
作者机构:
[Liu, Yu; He, Chuqi; Long, Dingxin; Zhao, Weichao; Yao, Jing; Mao, Liang] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.
通讯机构:
[Long, DX ; Zhao, WC] U
Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Circadian rhythms;Low-dose radiation;Melatonin, Oxidative stress;Zebrafish
期刊:
Aquatic Toxicology
ISSN:
0166-445X
年:
2024
卷:
276
页码:
107106
基金类别:
Department of Environmental Protection of Hunan Province [2023JJ30497]; [HBKT-2022021]
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
Ionizing radiation, as an increasingly serious environmental pollutant, has aroused widespread public concern. Melatonin, as an indole heterocyclic compound, is known to have anti-inflammatory and antioxidant effects. However, few studies have considered the comprehensive impact of melatonin on radiation damage. In this study, we used zebrafish as experimental materials and employed methods such as acridine orange staining, enzyme-linked immunosorbent assay (ELISA), video tracking for automated behavior analysis, microscope imaging, and real-ti...

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