期刊论文

N-无保护苯胺电化学硒醚化反应构建4-(烃基硒代)苯胺

Chen, J.;He, W.

中文

有机化学

0253-2786

2021

41

12

4766-4772

10.6023/cjoc202109044

* Corresponding authors. E-mail: weiminhe2016@yeah.net; 751589512@qq.com Received September 28, 2021; revised October 30, 2021; published online November 3, 2021. Project supported by the National Natural Science Foundation of China (Nos. 21902014, 22002037) and the Scientific Research Hunan Provincial Education Department (No. 19A068). 国家自然科学基金(Nos. 21902014, 22002037)、湖南省教育厅科学研究(No. 19A068)资助项目.

本校为其他机构

报道了一种无过渡金属催化剂、无化学氧化剂条件下N-无保护苯胺的电化学硒醚化反应.该反应在非分隔电解槽中进行,实现了温和电化学条件下4-(芳基硒代)苯胺和4-(烷基硒代)苯胺化合物的高效合成.该反应具有良好的官能团兼容性和易放大等优点,为合成4-(烃基硒代)苯胺类化合物提供了绿色实用的合成方法.

A transition-metal-free and chemical oxidant-free method was developed for the uniform synthesis of 4-arylselanylanilines and 4-alkylselanylanilines through electrolytic selenylation of N-unprotected anilines with diorganyl diselenides under mild conditions in an undivided cell. The present approach had good functional group compatibility, which made it to be a green and practical method to synthesize 4-(organylselanyl)anili...