In an attempt to discover novel compounds with high activity and low toxicity, a series of new 1-[2-(2,4-dichlorophenoxyl)acetyl]-5-amino-1H-pyrazole derivatives 3a-3j and 4a-4d have been designed and synthesized by the reaction of 2,4-dichlorophenoxylacetyl chloride with 5-amino-1H-pyrazole. The structures of all new compounds were confirmed by elemental analyses, 1H NMR, IR and MS spectroscopies. The results of preliminary bioassay indicate that compounds 3a-3j and 4a-4d possess high herb...