期刊论文

Chen, Xi;Mo, Zhong-cheng

英文

Clinica Chimica Acta

0009-8981

2019

497

54-60

10.1016/j.cca.2019.07.013

The process of spermatogenesis is deficient in the testis of VAD rats by several major factors: failure of A2 sperm to form from A1 spermatogonia, delayed precursor cell development and dysplasia, and reduced spermatids [31]. Studies have demonstrated that certain receptors that are present in the early GCs of neonatal testes allow for the necessary components to respond to RA signaling pathways, including RA receptors and retinoid receptors [33]. RA is poorly transported in the serum and

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Male fertility depends on the regulatory balance between germ cell self-renewal and differentiation, and the spatial and temporal patterns of this balance must be maintained throughout the life cycle. Retinoic acid and its receptors are important factors in spermatogenesis. Spermatogonia cells can self-proliferate and differentiate and have unique meiotic capabilities; they halve their genetic material and produce monomorphic sperm to pass genetic material to the next generation. A number of studies have found that the spermatogenesis process i...