期刊论文

Li, ZY

英文

FRONTIERS IN IMMUNOLOGY

1664-3224

2024

15

1289644

10.3389/fimmu.2024.1289644

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Natural Science Foundation of China (No. 82272383, and 32070189), Hunan Provincial Natural Science Foundation of China (No.2021JJ30594), Scientific Research Project of Hunan Provincial Health Commission (No. C202304127239).

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Chlamydia trachomatis, is a kind of obligate intracellular pathogen. The removal of C. trachomatis relies primarily on specific cellular immunity. It is currently considered that CD4(+) Th1 cytokine responses are the major protective immunity against C. trachomatis infection and reinfection rather than CD8(+) T cells. The non-specific immunity (innate immunity) also plays an important role in the infection process. To survive inside the cells, the first process that C. trachomatis faces is the innate immune response. As the "sentry" of the body...