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miRNA profiling in autism spectrum disorder in China

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成果类型:
期刊论文
作者:
Huang, Fengzhen;Zhou, Tieqiao;Yao, Xiaoxi;Yi, Jiping;Zhou, Fei;...
通讯作者:
Hong Jiang
作者机构:
[Huang, Fengzhen; Yi, Jiping; Yao, Xiaoxi; Zhou, Fei] Department of Neurology & Institute of Translational Medicine at University of South China, The First People's Hospital of Chenzhou, Chenzhou, Hunan 423000, PR China
[Zhou, Tieqiao] Department of Laboratory Medicine & Institute of Translational Medicine at University of South China, The First People's Hospital of Chenzhou, Chenzhou, Hunan 423000, PR China
[Hou, Xuan; Chen, Zhao; Wang, Chunrong; Long, Zhe; Jiang, Hong] Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China
通讯机构:
[Hong Jiang] D
Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China
语种:
英文
关键词:
MiRNA;MiRNA microarray;qRT-PCR
期刊:
Genomics Data
ISSN:
2213-5960
年:
2015
卷:
6
页码:
108-109
基金类别:
This study was supported by the National Basic Research Program (973 Program) (Nos. 2012CB944601 , 2012CB517902 and 2011CB510002 to Hong Jiang), the National Natural Science Foundation of China (Nos. 81410308019 , 81471156 , 81271260 , 30971585 to Hong Jiang; No. 31401135 to Rong Qui), Hunan Funds for Distinguished Young Scientist (No. 14JJ1008 to Hong Jiang), Xinjiang Natural Science Foundation (No. 201318101-4 to Hong Jiang), Natural Science Foundation of Hunan Province (No. 2012SK3194 to Wei Zhuang), the Undergraduate Innovation Project of Central South University (No. YB13028 , 201410533324 to Hong Jiang), Graduate Innovation Project of Central South University (No. 2014zzts078 to Zhao Chen), Research project of the First People's Hospital of Chenzhou (No. N2014-017 , to Fengzhen Huang) and High-level medical personel of Hunan province “225” Project.
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Autism spectrum disorder (ASD) is a clinically complex and heterogeneous disorder. It is characterized by impaired social abilities, disordered language, isolated areas of interest, and repetitive behaviors. Evidence suggested that the neuropathology of ASD is widely distributed, involving epigenetic regulation in the brain. MiRNAs are a group of endogenous non-coding RNAs that play a critical role in neurodevelopment, neuroplasticity, and other fundamental neurobiological processes. To study miRNA profiling in Autism spectrum disorder in China...

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