Natural Science FoundationNational Natural Science Foundation of China (NSFC) [09JJ6044]; Science and Technology Projects of Hunan Province [2008TP4038-2]; Scientific Research Innovation Project of Postgraduate [2008CXJJ04]; Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Human Province, China [2008-244]
机构署名：
本校为第一且通讯机构
院系归属：
医学院
摘要：
Recent evidence indicates that hydrogen sulfide (H2S) exerts an antiatherogenic effect, but the mechanism is unclear. Formation of macrophage-derived foam cells is a crucial event in the development of atherosclerosis. Thus, we explore the effect of H2S on the formation of macrophage-derived foam cells. Incubation of monocyte-derived macrophages with oxidized LDL (oxLDL) alone caused significant increases both in intracellular lipids revealed by Oil-red O staining and in intracellular total cholesterol (TC) and esterified cholesterol (EC) conce...
