期刊论文

Min-hu Chen<&wdkj&>Ying-lian Xiao

英文

Journal of Gastroenterology and Hepatology

0815-9319

2022

37

11

2060-2066

10.1111/jgh.16000

: The authors declare that they have no conflict of interest. : YL Xiao and MH Chen took a major lead in study conception and design, analysis and interpretation of data, critical revision of the article for important intellectual content, and final approval of the article. ND Tan played a major role in acquisition of data, interpretation of data, and drafting and finalizing the manuscript. The other authors took part in interpretation of data and critical revision of the final manuscript. All authors approved the final version of the manuscript. Guarantor of the article: YL Xiao and MH Chen.

本校为其他机构

Abstract Background and Aim Considering the limitation of varying acid suppression of proton pump inhibitors, this study was aimed to assess the efficacy, safety, and dose–effect relationship of keverprazan, a novel potassium‐competitive acid blocker, in the treatment of duodenal ulcer (DU) compared with lansoprazole. Methods A randomized, double‐blind, double‐dummy, multicenter, low‐dose, high‐dose, and positive‐drug parallel‐controlled study was conducted to verify the non‐inferiority of keverprazan (20 or 30 mg) to lansoprazole of 3...