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Pd-Pt-Ru nanozyme with peroxidase-like activity for the detection of total antioxidant capacity

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成果类型:
期刊论文
作者:
He, Jian;Yang, Lin;Zhang, Ying;Li, Ranhui;Wu, Jingjun;...
通讯作者:
He, Dongxiu(1025165380@qq.com);Wang, Weiguo(wang901234@163.com)
作者机构:
[Wang, Weiguo; Wu, Jingjun; Yang, Lin; He, Jian; Cao, Qianqian; He, Dongxiu; Li, Sang] Univ South China, Inst Pharm & Pharmacol, Hengyang 421000, Hunan, Peoples R China.
[Wang, Weiguo; Wu, Jingjun; Yang, Lin; He, Jian; Cao, Qianqian; He, Dongxiu; Li, Sang] Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Hengyang, Hunan, Peoples R China.
[Wang, Weiguo; Wu, Jingjun; Yang, Lin; He, Jian; Cao, Qianqian; He, Dongxiu; Li, Sang] Hunan Xinhexin Biol Med Co Ltd, Pharm Grad Educ Innovat Base, Hengyang, Hunan, Peoples R China.
[Li, Ranhui] Univ South China, Hengyang Med Sch, Inst Pathogen Biol, Hengyang 421000, Hunan, Peoples R China.
[Wu, Xian; Duan, Yunfeng] Hunan Prov Directly Affiliated TCM Hosp, Affiliated Hosp 1, Hunan Coll Tradit Chinese Med, Zhuzhou, Peoples R China.
通讯机构:
[Dongxiu He; Weiguo Wang] I
Institute of Pharmacy and Pharmacology, University of South China, Hengyang 421000, Hunan, China<&wdkj&>Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang, Hunan, China<&wdkj&>Hunan Xinhexin Biological Medicine Co., Ltd., Pharmacy Graduate Education Innovation Base, Hengyang, Hunan, China
语种:
英文
期刊:
ANALYTICAL METHODS
ISSN:
1759-9660
年:
2022
卷:
15
期:
1
页码:
8-16
基金类别:
This work was financially supported by the National Key Research and Development Program of China (2017YFC1703102); the Scientific Research Project of the Education Department of Hunan Province (20C1622 and 22A0318); the Natural Science Foundation of Hunan Province (2020JJ4521 and 2021JJ70115); the Hengyang Science and Technology Planning Project (2020hcjz6717); the Postgraduate Scientific Research Innovation Project of Hunan Province (QL20210230).
机构署名:
本校为第一机构
院系归属:
医学院
药学与生物科学学院
摘要:
The design of highly active nanozymes and the establishment of ultra-sensitive bioassays remain a challenge. Therefore, it is necessary to synthesize highly active nanozymes. In this work, a Pd-Pt-Ru (PPR) nanozyme was prepared by atomic coating of the bimetallic nanozyme Pd-Pt. The steady-state kinetics showed that the PPR nanozyme had excellent peroxidase-like activity. Based on this concept, the as-prepared PPR nanozyme was applied to the detection of ascorbic acid (AA) and hydrogen peroxide (H2O2). The linear ranges for ascorbic acid and hy...

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