期刊论文

CHANGES OF HISTORMORPHOLOGICAL AND MDA,SOD OF LUNG TISSUES OF RATS EXPOSED TO COF.

中文

现代预防医学

1003-8507

1999

1

23-25

湖南省教委资助

本校为第一机构

利用动式吸入烹调油烟持续染毒６０天制动动物模型观察肺部病理形态改变，并通过分光光度法测试肺组织匀浆Ｓ９中的ＭＤＡ、ＳＯＤ，探讨其损伤机理，结果表明：ＣＯＦ染毒组肺组织病理形态改变以炎症改变为主，尚有肺泡上皮腺样化生，不典型腺样增生病变形成。

Objective:Spranque dawley(SD) rats were exposed to subacute dose cooking oil fume(COF) in order to observe pathological changes of lung tissues.To reveal its machanisms,the concentration of malondialdehyde(MDA),the activities of superoxide dismutase(SOD) in Lung of SD rats were tests.Mathods:Rats of test group and negative group inhaled COF ((43±4)mg/m 3×30min/d×60d) and hot air (30min/d×60d) respectively,while positive control group was injected B(a)P from trachea (12mg/(kg·5d)×60d).Spectrophotometry colorimetry was made to investigate t...