期刊论文

Luo, Z.Q.

中文

临床耳鼻咽喉头颈外科杂志

2096-7993

2000

14

2

81-82

10.3969/j.issn.1001-1781.2000.02.014

卫生部优秀科技人才专项基金!(1995-144号) 国家教委留学回国人员科技基金!(1996-644号)

本校为其他机构

目的20:观察205-羟色胺20（205-20HT）对耳蜗微循环的影响。方法20:在豚鼠圆窗膜置放20220μl020.5%的5-20HT,以激光多普勒流量仪20（20LDF）测量耳蜗微循环的203个参数20:血流量20（20CBF）、运动的血细胞的数目20（20CMBC）、血流速度20（20Veloc）的变化20;以压力传感器测量平均动脉血压20（20MABP）的变化。结果20:耳蜗微循环出现了两个时期的变化20:第一时期迅速下降形成陡峰20,各参数的峰值为20CBF:86.8%20,CMBC:9020.220%20,Veloc:96.3%20;第二时期呈持续平稳变化20,其中20CBF、CMBC持续平稳地下降20,Veloc无明显变化。耳蜗微循环的平均变化为20CBF:89.7%20;CMBC:89.6%20;Veloc:12002002...

OBJECTIVE: The present study was undertaken to investigate the influence of serotonin (5-HT) on cochlear microcirculation. METHOD: 2 microliters 0.5% 5-HT were applied to round window membrane in anaesthetized guinea pigs. The three parameters as blood flow (CBF), number of blood cell moving (CMBC) and blood velocity (Veloc) of cochlear microcirculation were measured with laser doppler flowmeter. The mean arterial pressure (MABP) was recorded simultaneously. RESULT: 5-HT induced a biphasic response of reduction in cochlear blood flow. In the first phase, cochlear microcirculation showed a tran...