Molecular Fluorescent Probes for Liver Tumor Imaging

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成果类型：

期刊论文

作者：

Liu, Qian;Huang, Jia;He, Longwei;Yang, Xuefeng*;Yuan, Lin;...

通讯作者：

Yang, Xuefeng;Cheng, D;Yang, XF

作者机构：

[Cheng, Dan; Liu, Qian; Yang, Xuefeng; Huang, Jia] Univ South China, Hengyang Med Sch, Affiliated Nanhua Hosp,Clin Res Inst, Hunan Prov Clin Res Ctr Metab Associated Fatty Li, Hengyang 421002, Hunan, Peoples R China.

[Yang, Xuefeng] Univ South China, Hengyang Med Sch, Affiliated Nanhua Hosp, Dept Gastroenterol, Hengyang 421002, Hunan, Peoples R China.

[He, Longwei] Univ South China, Hengyang Med Sch, Dept Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang, Peoples R China.

[Cheng, Dan; Yuan, Lin] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Mol Sci & Biomed Lab, Changsha 410082, Peoples R China.

通讯机构：

[Cheng, D ; Yang, XF ; Yang, XF] U

Univ South China, Hengyang Med Sch, Affiliated Nanhua Hosp,Clin Res Inst, Hunan Prov Clin Res Ctr Metab Associated Fatty Li, Hengyang 421002, Hunan, Peoples R China.

Univ South China, Hengyang Med Sch, Affiliated Nanhua Hosp, Dept Gastroenterol, Hengyang 421002, Hunan, Peoples R China.

Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Mol Sci & Biomed Lab, Changsha 410082, Peoples R China.

语种：

英文

关键词：

fluorescent probe;liver tumor;activatable probe;bioimaging;biomaker

期刊：

CHEMISTRY-AN ASIAN JOURNAL

ISSN：

1861-4728

年：

2022

卷：

期：

页码：

e202200091-

DOI：

10.1002/asia.202200091

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21904035]; Science and Technology Project of Hunan Province [2021RC3108]; Special Funding for the Construction of Innovative Provinces in Hunan [2021SK4031]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2020T130184]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Liver cancer is a malignant tumor with both high morbidity and mortality. The traditional treatment method is mainly based on hepatectomy for liver tumor. However, it is difficult to accurately distinguish the tumor tissue and its boundary with the naked eye and palpation, leading to an ambiguous resection result, finally causing high recurrence of liver cancer. Molecular fluorescent probes possessing numerous advantages, such as non-invasiveness, high sensitivity, and real-time imaging, have been extensively studied in liver cancer imaging and...

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Molecular Fluorescent Probes for Liver Tumor Imaging

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