Exosome is a Fancy Mobile Sower of Ferroptosis

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成果类型：

期刊论文

作者：

Hou, Qin;Ouyang, Siyu;Xie, Zhongcheng;He, Yinling;Deng, Yunong;...

通讯作者：

Peng, Tianhong;Xie, W;Li, L

作者机构：

[Hou, Qin] Univ South China, Inst Cardiovasc Res,Key Lab Atherosclerol Hunan Pr, Med Res Ctr,Hunan Prov Cooperat Innovat Ctr Mol Ta, Key Lab Atherosclerol Hunan Prov,Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Deng, Yunong; Guo, Jiamin; Li, Pin; Yu, Panpan; Xie, Zhongcheng; He, Yinling; Ma, Wentao; Ouyang, Siyu; Tan, Xiaoqian; Lin, Xiaoyan; Liu, Zhiyang] Univ South China, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Zhang, Zhixia; Mo, Qinger; Yu, Jiang; Chen, Dandan] Univ South China, Hengyang Med Sch, Class Clin Med, Hengyang 421001, Hunan, Peoples R China.

[Chen, Xi; Xie, Wei; Peng, Tianhong; Peng, TH] Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Li, Liang] Univ South China, Hengyang Med Sch, Dept Physiol, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Xie, W ; Li, L ; Peng, TH] U

Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Hengyang Med Sch, Dept Physiol, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Exosome;Ferroptosis;Lipid peroxidation;Oxidative stress;MicroRNAs

期刊：

Journal of Cardiovascular Translational Research

ISSN：

1937-5387

年：

2024

卷：

期：

页码：

1067-1082

DOI：

10.1007/s12265-024-10508-8

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Exosomes, nano-sized small extracellular vesicles, have been shown to serve as mediators between intercellular communications by transferring bioactive molecules, such as non-coding RNA, proteins, and lipids from secretory to recipient cells, modulating a variety of physiological and pathophysiological processes. Recent studies have gradually demonstrated that altered exosome charges may represent a key mechanism driving the pathological process of ferroptosis. This review summarizes the potential mechanisms and signal pathways relevant to ferroptosis and then discusses the roles of exosome in...

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