Traumatic brain injury (TBI) is one of the common diseases diagnosed in departments of neurosurgery. Apolipoprotein E (apoE) can improve the prognosis of TBI. In this study, we aimed to explore the effect of apoE in mechanically damaging neurons as well as its underlying molecular mechanism. Western blot analysis and immunofluorescence assay was performed to detect the expressions of associated proteins. The expressions of apoE, p38, and phosphorylation of P38 were increased in mechanically injured neurons compared with those of the non-injured...
