期刊论文

中文

中国组织工程研究

2095-4344

2011

15

4

757-760

10.3969/j.issn.1673-8225.2011.04.046

the Science and Technology Planning Project of Shenzhen,No.200702043~~；

本校为第一机构

背景:以往研究显示,酸性成纤维细胞因子（acidic fibroblast growth factor,aFGF）复合部分脱蛋白骨（partially deproteinised bone,PDPB）对实验动物早期股骨头缺血坏死血管再生具有良好的促进作用,但其组织学变化尚不明确。目的:从组织学变化角度观察 aFGF 复合PDPB 修复兔早期股骨头缺血坏死的效果。方法:用新西兰大白兔制备早期股骨头缺血坏死动物模型,建模后随机分为空白组、PDPB 组和 aFGF/PDPB 组。PDPB 组植入PDPB,aFGF/PDPB 组植入 aFGF/PDPB。所有动物分别于第 2,4,8 周取材进行苏木精伊红染色观察成骨情况。结果与结论:空白组第 8 周缺损区被纤维结缔组织填充,在交界处有少量骨样组...

BACKGROUND： Previous studies have demonstrated that acidic fibroblast growth factor （aFGF） combined with partially deproteinized bone （PDPB） （aFGF/PDPB） well promotes vascularization in animals with early-stage avascular necrosis of the femoral head （ANFH）, but the histological results remain unknown. OBJECTIVE： To observe the histological repairing effects of aFGF/PDPB on early-stage ANFH in rabbits. METHODS： New Zealand rabbits were established models of bilateral ANFH and were randomly divided into a blank group, a simple PDPB gro...