期刊论文

中文

生命科学

1004-0374

2023

35

02

212-219

湖南省自然科学基金项目(2022JJ30513) 南华大学研究生科研创新项目(223YXC023) 南华大学大学生创新创业训练计划项目(2022X10555134)。

本校为第一机构

SIRT6是Sirtuins家族的一员，因具有脱乙酰酶活性而参与调节能量代谢、衰老、肥胖、胰岛素抵抗、炎症等众多生物学过程。最近的研究发现SIRT6还能通过保护内皮细胞和血管平滑肌细胞、抗炎及调节脂质代谢等发挥抑制动脉粥样硬化发生发展的作用。该文就SIRT6在动脉粥样硬化方面的研究进展进行综述。

SIRT6,a member of the Sirtuins family,is involved in many biological processes such as regulation of energy metabolism,aging,obesity,insulin resistance,and inflammation due to its deacetylase activity.Recent studies have found that SIRT6 can also inhibit the development...MORE SIRT6,a member of the Sirtuins family,is involved in many biological processes such as regulation of energy metabolism,aging,obesity,insulin resistance,and inflammation due to its deacetylase activity.Recent studies have found that SIRT6 can also inhibit the development of atherosclerosis by protecting endothelial cells ...