期刊论文

Research progress of the relationship between vitamin D and metabolic inflammation

中文

生命科学

1004-0374

2019

31

10

1060-1068

10.13376/j.cbls/2019131

湖南省自然科学基金项目（2018JJ2341）； 南华大学大学生研究性学习和创新性实验计划项目（2018-118）；

本校为第一机构

维生素D （vitamin D, VitD）是一类固醇类衍生物,活性维生素D通过与维生素D受体（VDR）结合发挥多种生物学功能,除了与骨骼的生长发育相关之外,其对脂肪、肝脏及肾脏等多种组织器官的功能具有重要的调节作用。肥胖诱导的代谢性炎症与心血管疾病、糖尿病、代谢综合征等疾病密切相关,然而,维生素D与肥胖引发的代谢性炎症是否有直接的联系尚不明确。为此,该文对维生素D与代谢性炎症之间的关系作综述,以便揭示维生素D在代谢性炎症防治中的作用。

Vitamin D (VitD) is a steroid derivative. Activated vitamin D exerts various biological functions by binding to vitamin D receptor (VDR). In addition to being associated with bone growth and development, it has an important regulatory effect on the functions of various tissues and organs such as fat, liver and kidney. Obesityinduced metabolic inflammation is closely related to diseases such as cardiovascular diseases, diabetes, and metabolic syndrome. However, it is not clear whether vitamin D is directly related to the metabolic inflammation caused by obesity. Therefore, this article reviews ...