期刊论文

Effect of autologous platelet plasmapheresis and reinfusion on acute kidney injury after total aortic arch replacement

Huang, Z.

中文

中华麻醉学杂志

0254-1416

2021

41

5

532-536

10.3760/cma.j.cn131073.20201217.00506

Knowledge Innovation Program on Basic Research Project of Shenzhen Science and Technology Innovation Commission JCYJ20170307161610240

本校为其他机构

目的:评价自体血小板分离(APP)回输对全弓置换术患者术后急性肾损伤的影响。方法:选择全麻下拟行全弓置换术患者60例，性别不限，年龄18～64岁，BMI 19～34 kg/m 2，ASA分级Ⅲ或Ⅳ级。采用随机数字表法分为3组( n＝20)：APP回输组(A组)、急性等容血液稀释组(N组)和单纯自体血回收回输组(C组)。A组于手术开始前完成APP，浓缩红细胞根据术中情况及时回输，贫血小板血浆和富血小板血浆待鱼精蛋白中和后回输；N组在手术开始前完成急性等容血液稀释(ANH)，放出的全血待鱼精蛋白中和后回输；C组在术中单纯行自体血回收及洗涤红细胞回输，A组和N组均行自体血回收。分别于麻醉诱导后10 min(T 1)、体外...

Objective:To evaluate the effect of autologous platelet plasmapheresis (APP) and reinfusion on acute kidney injury (AKI) after total aortic arch replacement.Methods:Sixty American Society of Anesthesiologists physical status Ⅲ or Ⅳ patients of both sexes, aged 18-64 yr, with body mass index of 19-34 kg/m 2, scheduled for total aortic arch replacement under general anesthesia, were divided into 3 groups( n=20 each)using a random number table method: APP-reinfusion group (group A), acute normovolemic hemodilution (ANH) group (group N) and aut...