期刊论文

中文

中国药房

1001-0408

2011

22

27

2511-2514

广州市科技攻关重点项目（2003A30904）；

本校为其他机构

目的:研究蛞蝓冻干粉对慢性支气管炎的改善作用。方法:运用二氧化硫(SO2)刺激法复制小鼠慢性支气管炎模型,观察蛞蝓冻干粉的止咳作用;采用气管段酚红法观察蛞蝓冻干粉的祛痰作用;运用气管内注入脂多糖(PLS)法复制大鼠慢性支气管炎模型,采用喷雾致喘法观察蛞蝓冻干粉的平喘作用;取气管及肺组织,观察大体标本的情况,然后切片并行HE染色,观察蛞蝓冻干粉对慢性支气管炎模型大鼠肺部炎症病理改变的影响。结果:高、中剂量蛞蝓冻干粉能显著延长慢性支气管炎小鼠的咳嗽潜伏期,减少咳嗽次数(P

OBJECTIVE：To study the improvement effect of Limax lyophilized powder on chronic bronchitis.METHODS：The stimulation of sulfur dioxide（SO2） was adopted to make the mice models of chronic bronchitis to evaluate the cough-relieving effect of Limax lyophilized powder.Meanwhile,the expectorant effect of Limax lyophilized powder was observed by comparing the excretion quantity of phenolphthalein in mice＇s trachea.Chronic bronchitis rat model was established by intratracheal injection of lipopolysaccharide（LPS） to investigate the asthma-relievi...