Objective: To investigate the anti-mutagenicity of the extracts of Yunnan pincones. Methods: Horsebeans from Dengchuan village and Wanqiao village were divided into 4 groups randomly. After the pretreatment, vicia-micronucleus test was applied to explore the anti-mutagenicity of the extracts of pinecones. Results: The extract I of Yunnan pinecone showed 50% inhibition on the Dengchuan fava beans-induced micronucleus, 62.5% inhibition on cyclophosphamide-induced micronucleus and 50% inhibition on Wanqiao lava beans root-induced micronucleus. ...