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Mucinous histology is associated with poor prognosis in locally advanced colorectal adenocarcinoma treated with postoperative first-line adjuvant chemotherapy: A systematic review and meta-analysis

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成果类型:
期刊论文
作者:
Zhang, Yiwei;Chen, Yuqiao;Huang, Jia;Wu, Xiaofeng;Tang, Rong;...
通讯作者:
Peng, X.;Xiao, S.;Fu, K.
作者机构:
[Peng, Xiuda; Xu, Yunhua; Xiao, Shuai; Zhang, Yiwei; Huang, Jia] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Canc Res Inst, Hengyang 421001, Hunan, Peoples R China.
[Fu, Kai; Chen, Yuqiao] Cent South Univ, Inst Mol Precis Med, Dept Gen Surg, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China.
[Fu, Kai; Chen, Yuqiao] Cent South Univ, Hunan Key Lab Mol Precis Med, Dept Gen Surg, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China.
[Wu, Xiaofeng; Xiao, Shuai; Tang, Rong; Huang, Qiulin] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Gastrointestinal Surg, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Xiuda Peng; Shuai Xiao] T
The First Affiliated Hospital, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China<&wdkj&>The First Affiliated Hospital, Department of Gastrointestinal Surgery, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China<&wdkj&>The First Affiliated Hospital, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China
语种:
英文
关键词:
Colorectal carcinoma;Mucinous adenocarcinoma;Postoperative adjuvant chemotherapy;Meta-analysis
期刊:
European Journal of Surgical Oncology
ISSN:
0748-7983
年:
2022
卷:
48
期:
10
页码:
2075-2081
基金类别:
This work was supported by the Clinical Medical Technology Innovation Project of Hunan Province ( 2020SK51815 ), the Scientific Research Fund Project of Hunan Provincial Health Commission ( 20201919 , 202104010105 ) and N atural Science Foundation of Hunan Province ( 2022JJ30538 ).
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Purpose: Postoperative adjuvant chemotherapy followed surgery is the standard management for localized advanced colorectal carcinoma (CRC). Mucinous adenocarcinoma (MAC) is a peculiar histological subtype of CRC, but the prognosis of MAC patients is controversial. The objective of this study is to assess the implication of MAC in survival of patients treated with surgery and firs-line adjuvant chemotherapy. Methods: Studies describing outcomes for advanced MAC and non-specific adenocarcinoma (AC) of CRC patients treated with first-line postoper...

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