Cardiovascular disease (CVD) has been one of the leading causes of mortality worldwide, and atherosclerosis (As) is a common pathogenic basis for CVD. Xuezhikang is a purified extract of fermented red yeast rice with benefits to improvement of As. Apart from being a safe and effective lipid-lowering drug, Xuezhikang has drawn growing awareness due to its cardiovascular protection beyond lipid modulation. Studies have shown that Xuezhikang exerts its anti-atherosclerotic function via mechanisms as the following: regulation of endothelial functio...