Molecular diagnosis of HIV and relevant novel technologies in mutation analysis

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成果类型：

期刊论文

作者：

Xiao, L.;Zhang, J.;Yin, Y. F.;Chen, C. L.;Li, Kai;...

通讯作者：

Zhang, I

作者机构：

[Xiao, L.; Li, Kai] Suzhou Univ, Mol Med Ctr, Suzhou 215006, Peoples R China.

[Xiao, L.; Li, Kai] Suzhou Univ, Second Affilated Hosp, Suzhou 215006, Peoples R China.

[Xiao, L.; Zhang, J.; Chen, C. L.; Li, Kai] Nanhua Univ, SNP Inst, Hengyang, Hunan, Peoples R China.

[Zhang, J.] Novartis Res Fdn, Genom Inst, San Diego, CA USA.

[Yin, Y. F.] City Hope Natl Med Ctr, Duarte, CA 91010 USA.

通讯机构：

[Zhang, I ]

Nanhua Univ, SNP Inst, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

HIV;Molecular diagnosis;Mutation;Viral load

期刊：

Biotechnology Advances

ISSN：

0734-9750

年：

2008

卷：

期：

页码：

389-397

DOI：

10.1016/j.biotechadv.2008.04.007

基金类别：

This paper is partially supported by a combined grant from the Hunan Provincial grant (04A048) and Chinese Education Ministry (205106), and a Chinese National 863 Major grant (2007AA02Z4A7).

机构署名：

本校为通讯机构

院系归属：

药学与生物科学学院

摘要：

HIV infection is one of the major threats to human health due to the lack of relevant vaccine and drugs to cure AIDS. Its early diagnosis is thus important in controlling HIV transmission. Molecular diagnosis of HIV can be performed qualitatively and quantitatively. Currently, molecular diagnosis of HIV infection is only used as a complementary diagnosis although viral load test is used to monitor disease progression and responsiveness to antiviral therapy. To optimize HIV assays, a variety of technological advances, such as the introduction of...

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Molecular diagnosis of HIV and relevant novel technologies in mutation analysis

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