版权说明 操作指南
首页 > 成果 > 详情

Molecular diagnosis of HIV and relevant novel technologies in mutation analysis

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Xiao, L.;Zhang, J.;Yin, Y. F.;Chen, C. L.;Li, Kai;Chang, A.;Sirois, P.
通讯作者:
Zhang, I
作者机构:
[Xiao, L.; Li, Kai] Suzhou Univ, Mol Med Ctr, Suzhou 215006, Peoples R China.
[Xiao, L.; Li, Kai] Suzhou Univ, Second Affilated Hosp, Suzhou 215006, Peoples R China.
[Xiao, L.; Zhang, J.; Chen, C. L.; Li, Kai] Nanhua Univ, SNP Inst, Hengyang, Hunan, Peoples R China.
[Zhang, J.] Novartis Res Fdn, Genom Inst, San Diego, CA USA.
[Yin, Y. F.] City Hope Natl Med Ctr, Duarte, CA 91010 USA.
通讯机构:
[Zhang, I ] Nanhua Univ, SNP Inst, Hengyang, Hunan, Peoples R China.
Nanhua Univ, SNP Inst, Hengyang, Hunan, Peoples R China.
语种:
英文
关键词:
Molecular diagnosis;HIV;Viral load;Mutation
期刊:
Biotechnology Advances
ISSN:
0734-9750
年:
2008
卷:
26
期:
5
页码:
389-397
机构署名:
本校为通讯机构
院系归属:
药学与生物科学学院
摘要:
HIV infection is one of the major threats to human health due to the lack of relevant vaccine and drugs to cure AIDS. Its early diagnosis is thus important in controlling HIV transmission. Molecular diagnosis of HIV can be performed qualitatively and quantitatively. Currently, molecular diagnosis of HIV infection is only used as a complementary diagnosis although viral load test is used to monitor disease progression and responsiveness to antiviral therapy. To optimize HIV assays, a variety of technological advances, such as the introduction of dUTP/UNG system, real-time detection platform, and coupling of more than one enzyme in molecular identification, have been integrated into new methods. With the development of more reliable HIV assays in the future, the molecular diagnosis of HIV is expected to be accepted as one of the standards in determining whether there is a HIV infection in resource-rich laboratories, which will play a crucial role in reducing HIV transmission. ©2008 Elsevier Inc. All rights reserved.

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com