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The roles of E2F7 in cancer: Current knowledge and future prospects

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成果类型:
期刊论文
作者:
Chen, Ke-qian;Lei, Hai-bo*;Liu, Xiang;Wang, Shu-zhi
通讯作者:
Lei, Hai-bo;Liu, X;Wang, SZ
作者机构:
[Lei, Hai-bo; Lei, HB; Liu, Xiang; Chen, Ke-qian] Xiangtan Cent Hosp, Dept Clin Pharm, Xiangtan 411100, Peoples R China.
[Wang, Shu-zhi; Chen, Ke-qian] Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang Med Sch, Hengyang 421001, Peoples R China.
[Wang, Shu-zhi; Wang, SZ] Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.
通讯机构:
[Lei, HB; Liu, X ] X
[Wang, SZ ] U
Xiangtan Cent Hosp, Dept Clin Pharm, Xiangtan 411100, Peoples R China.
Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Biological function;Cancer;DNA damage;E2F7;Transcription
期刊:
Heliyon
ISSN:
2405-8440
年:
2024
卷:
10
期:
14
页码:
e34362
机构署名:
本校为通讯机构
院系归属:
药学与生物科学学院
摘要:
BACKGROUND: E2F7 is a recently discovered member of the E2F family. Investigating the function and mechanism of E2F7 in the growth of tumors is significant for the clinical diagnosis and therapy of these malignancies. OBJECTIVE: The purpose of this review is to provide theoretical basis for the diagnosis and treatment of malignant tumors by exploring E2F7. METHODS: The relevant information was collected through the PubMed database using keyword searches "E2F7" and "cancer". RESULTS: On the one hand, E2F7 plays an essential role in embryonic development, angiogenesis, and the nervous system. On...

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