This research was supported by the National Natural Science Foundation of China (11405081), the Hunan Provincial Natural Science Foundation of China (2017JJ3276) and the Department of Education of Hunan Province (17B226).
机构署名：
本校为第一且通讯机构
院系归属：
化学化工学院
摘要：
The authors describe an ultrasensitive amperometric enzymatic assay for uranyl ion. Itis based on the use of mesoporous silica nanoparticles (mesoSiNPs) loaded with Methylene Blue (MB) and functionalized with an UO2(II)-dependent DNAzyme. The electroactive label MB was sealed in the inner pores of the mesoSiNPs along with double stranded DNA (containing the DNAzyme and the substrate strand). In the presence of UO2(II), the DNAzyme is actived to cleave the substrate strands. This leads to the cleavage of the caps and the release of MB from the m...
