[Gao, Yongchao; Zhang, Wei; Chen, Xiaoping; Sun, Bao] Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha 410078, Peoples R China.

[Sun, Bao] Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha 410011, Peoples R China.

[Sun, Bao] Cent South Univ, Inst Clin Pharm, Changsha 410011, Peoples R China.

[Zhou, Jiecan] Univ South China, Affiliated Hosp 1, Inst Clin Med, Hengyang 421001, Peoples R China.

[Gao, Yongchao; Zhang, Wei; Chen, Xiaoping] Cent South Univ, Hunan Key Lab Pharmacogenet, Inst Clin Pharmacol, Changsha 410078, Peoples R China.

[Zhang, Wei; Chen, Ling] C

[Zhang, Wei] M

[Zhang, Wei] N

Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha 410078, Peoples R China.

Cent South Univ, Hunan Key Lab Pharmacogenet, Inst Clin Pharmacol, Changsha 410078, Peoples R China.

Minist Educ, Engn Res Ctr Appl Technol Pharmacogen, Changsha 410078, Peoples R China.

Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Peoples R China.

Cent South Univ, Xiangya Hosp, Dept Gastrointestinal Surg, Changsha 410078, Hunan, Peoples R China.

Genes;Glucose;Metabolism;Polymerase chain reaction;Proteins;Rats;C-jun N-terminal kinase;Death-inducing signaling complexes;Hepatic insulin resistance;Immunofluorescence assay;Immunohistochemistry;Immunoprecipitations;Protein-protein interactions;Quantitative real time PCR;Insulin;binding protein;Fas associated factor 1;glucose;insulin;lipid;reactive oxygen metabolite;stress activated protein kinase;unclassified drug;apoptosis regulatory protein;insulin;mitogen activated protein kinase kinase 4;animal cell;animal experiment;animal model;animal tissue;Article;controlled study;data analysis software;down regulation;enzyme activation;enzyme phosphorylation;flow cytometry;gain of function mutation;gene overexpression;gluconeogenesis;glucose transport;immunofluorescence test;immunohistochemistry;immunoprecipitation;insulin blood level;insulin resistance;insulin signaling;lipid diet;lipid storage;liver cell;liver disease;liver tissue;loss of function mutation;male;MAPK signaling;nonhuman;phenotype;protein expression;protein protein interaction;rat;real time polymerase chain reaction;upregulation;Western blotting;animal;insulin resistance;liver;metabolism;pathology;Accumulation;Genes;Glucose;Phosphorylation;Production;Proteins;Resistance;Transport;Animals;Apoptosis Regulatory Proteins;Insulin;Insulin Resistance;Liver;Male;MAP Kinase Kinase 4;MAP Kinase Signaling System;Rats

医学院