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Theoretical and Experimental Studies of the Dynamic Damage of Endothelial Cellular Networks Under Ultrasound Cavitation

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成果类型:
期刊论文
作者:
Xia, Chuangjian;Hu, Jiwen;Zhou, Kun;Li, Yingjie;Yuan, Sha;...
通讯作者:
Hu, JW
作者机构:
[Hu, JW; Li, Qinlin; Hu, Jiwen; Xia, Chuangjian; Yuan, Sha; Li, Yingjie] Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.
[Zhou, Kun] Univ South China, Hengyang Med Sch, Hengyang 421001, Peoples R China.
[Li, Qinlin; Yuan, Sha] Univ South China, Sch Elect Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Hu, JW ] U
Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Endothelial cells;Intercellular junctions;Cell–cell rupture;Cavitation damage
期刊:
Cellular and Molecular Bioengineering
ISSN:
1865-5025
年:
2024
页码:
1-14
基金类别:
National Natural Science Foundation of China [12274200, 11774088]; National Nature Science Foundation of China [202250045335]; Hengyang science and technology plan projects
机构署名:
本校为第一且通讯机构
院系归属:
电气工程学院
数理学院
摘要:
IntroductionThe interaction between endothelial cells can regulate hemostasis, vasodilation, as well as immune and inflammatory responses. Excessive loading on the endothelial cells leads to endothelial damage and endothelial barrier dysfunction. Understanding and mastering the dynamic nature of cell-cell rupture plays a crucial role in exploring the practical applications related to tumor destruction, vascular remodeling, and drug delivery by employing cavitation-induced damage to soft tissues.MethodsTo investigate the damage mechanisms of endothelial cellular networks under ultrasound cavita...

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