MCM-41 mesoporous silica nanoparticles(MSNs) have drawn a great deal of attention in biosensors,because of their specific structures and unique physical chemistry properties.Combined with various functional materials or molecules,such as DNA,signal probes and various active nanoparticles,MCM-41 MSNs can be developed into the multifunctional nanomaterials in the application of DNA biosensors.In particular,the spherical and porous film of MCM-41 MSNs have the advantages of high loading capacity,controlled release of pores and high specific surface area,which can effectively load various signal p...